Clinicians often rely on laboratory testing to find evidence of infections that may explain a patient’s symptoms and help guide treatment. Direct evidence may be a specific segment of DNA or a protein that confirms the presence of the target pathogen. Indirect evidence could be antibodies and other immune biomarkers that suggest recent or past [...]
Bartonella Digital ePCR™ is Now Available!
We are very excited to announce the launch of Bartonella Digital ePCR™. This advanced DNA test methodology provides the most sensitive direct detection for Bartonella species infections. Bartonella infections can cause a broad range of diseases, from acute cases of cat scratch disease and trench fever to culture negative endocarditis, rheumatologic disease, neurologic disease, vasoproliferative tumors, and [...]
Tick-and flea-borne disease risk is not one size fits all
Disease risk is determined by many factors that are often hard for researchers and clinicians to quantify. The prevalence of a pathogen may vary depending on region, but exposure does not necessarily lead to infection. Further, the severity of the disease following infection is not the same in every case. As seen with the COVID-19 [...]
Bartonella and Brucella: Cousins in the Bacteria Kingdom
Bartonella and Brucella are close cousins in the taxonomy that describes the relationships between all life. These bacteria developed out of a common ancestor. The extent of similarity in their genomes suggests that their division occurred relatively recently. They are both intracellular pathogens (i.e., they live inside the cells in their hosts) and can manipulate [...]
Don’t Let Your Flea- or Tick-borne Disease Journey Delay Medical Care for Other Conditions
Patients who are currently receiving medical care for flea- or tick-borne disease often bring us new symptoms and ask if they might be related to flea- or tick-borne infection. They are concerned that the role of infection might be downplayed or that their physician might simply not know much about the role of these infections [...]
Harnessing the Power of Sample Partitioning to Advance Bartonella Testing
Bartonella and a few other low-yield microbes pose significant challenges to conventional diagnostic testing. Healthcare providers who are familiar with illnesses caused by these pathogens will often clinically diagnose patients based on their exposure risks, travel history, and symptoms, but without laboratory confirmation. Why? Despite recent innovations, developing a diagnostic test that is 100% reliable [...]