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Pathogen Testing

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Bartonella and Brucella: Cousins in the Bacteria Kingdom

Bartonella and Brucella are close cousins in the taxonomy that describes the relationships between all life. These bacteria developed out of a common ancestor. The extent of similarity in their genomes suggests that their division occurred relatively recently. They are both intracellular pathogens (i.e., they live inside the cells in their hosts) and can manipulate [...]

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Some people tolerate infections better than others. Why?

News reporting on the COVID-19 pandemic is giving the public a crash course on the transmission and pathobiology of SARS-CoV-2. A major question still puzzling researchers is what causes some people to be asymptomatic while others experience debilitating symptoms. Many clues point towards the individual’s host immune response as well as his/her ability to accommodate [...]

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Don’t Let Your Flea- or Tick-borne Disease Journey Delay Medical Care for Other Conditions

Patients who are currently receiving medical care for flea- or tick-borne disease often bring us new symptoms and ask if they might be related to flea- or tick-borne infection. They are concerned that the role of infection might be downplayed or that their physician might simply not know much about the role of these infections [...]

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Harnessing the Power of Sample Partitioning to Advance Bartonella Testing

Bartonella and a few other low-yield microbes pose significant challenges to conventional diagnostic testing. Healthcare providers who are familiar with illnesses caused by these pathogens will often clinically diagnose patients based on their exposure risks, travel history, and symptoms, but without laboratory confirmation. Why? Despite recent innovations, developing a diagnostic test that is 100% reliable [...]

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Ruminant Bartonella species: What are they? Are they harmful?

Bartonella species are bacteria present in wild and domesticated animal populations throughout the world. It is important to be aware of the breadth of Bartonella species, including those associated with cows, sheep, deer, and other ruminants, because of their potential role in both animal and human disease. Research on the Bartonella genus over the past […]

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